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Cross-border reprogenetic services.

V Couture1, R Drouin, S-L Tan

  • 1Laboratory of Transdisciplinary Research in Genetics, Medicines and Social Sciences, Division of Genetics, Department of Pediatrics, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada.

Clinical Genetics
|May 7, 2014
PubMed
Summary
This summary is machine-generated.

Cross-border reprogenetic services involve international patient and embryo cell movement for pre-implantation genetic diagnosis. This review synthesizes knowledge on these services, highlighting unique concerns and governance issues.

Keywords:
genetic techniqueshealth care quality, access, and evaluationhistocompatibility testingmedical tourismpre-implantation genetic diagnosispre-implantation screeningsex pre-selection

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Area of Science:

  • Reproductive Medicine
  • Genetics
  • Medical Law & Ethics

Background:

  • International movement of patients and embryo cells for pre-implantation genetic diagnosis is increasing.
  • The phenomenon of 'cross-border reprogenetic services' remains poorly defined.
  • Existing evidence suggests significant implications for service provision, patient safety, and legal/social justice.

Purpose of the Study:

  • To synthesize current knowledge on the international movement of patients and embryo cells for pre-implantation genetic diagnosis.
  • To identify the specific nature and implications of 'cross-border reprogenetic services'.
  • To analyze themes related to scope, scale, motivations, concerns, and governance.

Main Methods:

  • Narrative overview protocol.
  • Thematic analysis of existing literature.
  • Synthesis of empirical and speculative evidence.

Main Results:

  • Five major themes emerged: scope, scale, motivations, concerns, and governance.
  • Cross-border reprogenetic services share themes with medical tourism but have unique characteristics.
  • Specific concerns include diagnostic risks, restrictions on controversial tests, and uncertain genetic counseling access.

Conclusions:

  • Cross-border reprogenetic services present unique challenges distinct from general medical tourism.
  • The diagnostic and autologous nature of reprogenetics amplifies risks like misdiagnosis.
  • Effective governance is needed to address ethical, legal, and social justice issues in cross-border reproductive genetics.