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Radiation-induced osteosarcoma of the hand: case report
Mark E Puhaindran1, Kendall Hamilton1, Stacy Schlumbohm1
1Department of Hand and Reconstructive Microsurgery, National University Hospital, Singapore; The Orthopaedic Surgery Residency Program, Grand Rapids Medical Education Partners, Grand Rapids, MI; Department of Pediatric Hematology/Oncology, Helen DeVos Children's Hospital, Grand Rapids, MI; Spectrum Health Medical Group, Grand Rapids, MI; Van Andel Research Institute, Grand Rapids, MI; Department of Surgery, Michigan State University College of Human Medicine, Grand Rapids, MI.
Abstract:
Radiation-associated sarcomas represent less than 5% of all sarcomas and can arise from previously irradiated bone or soft tissue. We report a case of radiation-associated osteosarcoma that developed in the hand of a patient who had previously been treated for synovial sarcoma. Despite aggressive, multimodality treatment, the disease progressed rapidly. This case highlights the need for patients and treating physicians to be aware of this potential complication of radiotherapy to the hand.
