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Antimicrobial polyurethane thermosets based on undecylenic acid: synthesis and evaluation
Cristina Lluch1, Braulio Esteve-Zarzoso, Albert Bordons
1Departament de Química Analítica i Química Orgànica, Universitat Rovira i Virgili, C/Marcel.lí Domingo s/n, 43007, Tarragona, Spain.
Abstract:
In the present study, plant oil-derived surface-modifiable polyurethane thermosets are presented. Polyol synthesis is carried out taking advantage of thiol-yne photopolymerization of undecylenic acid derivatives containing methyl ester or hydroxyl moieties. The prepared methyl ester-containing polyurethanes allow surface modification treatment to enhance their hydrophilicity and impart antimicrobial activity through the following two steps: i) grafting poly(propylene glycol) monoamine (Jeffamine M-600) via aminolysis and ii) Jeffamine M-600 layer complexation with iodine. The antimicrobial activity of the iodine-containing polyurethanes is demonstrated by its capacity to inhibit the growth of Staphylococcus aureus, and Candida albicans in agar media.
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