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Endobronchial non-Hodgkin's lymphoma
1Department of Internal Medicine, Tokyo Metropolitan Komagome Hospital, Bunkyo-ku, Japan.
Respiratory Medicine
|January 1, 1989
Summary
This case report details a rare instance of non-Hodgkin's lymphoma causing multiple endobronchial tumors, leading to lung collapse. Combination chemotherapy effectively treated these airway tumors.
Area of Science:
- Pulmonology
- Oncology
- Pathology
Background:
- Non-Hodgkin's lymphoma (NHL) is a diverse group of lymphoid malignancies.
- Endobronchial involvement by lymphoma is uncommon but can cause significant airway obstruction.
Observation:
- A 64-year-old male patient with diagnosed NHL presented with complete left upper lobe lung collapse.
- Fibreoptic bronchoscopy revealed numerous polypoid lymphoma tumors obstructing the trachea and bilateral bronchi.
- The left upper lobe bronchus was completely occluded by these endobronchial tumors.
Findings:
- The observed endobronchial tumors demonstrated a positive response to combination chemotherapy targeting the lymphoma.
- This case represents the seventh documented instance of non-Hodgkin's lymphoma manifesting with multiple endobronchial tumors.
Implications:
- Highlights the importance of considering lymphoma in the differential diagnosis of endobronchial masses, especially in patients with a known history of NHL.
- Demonstrates the potential efficacy of systemic chemotherapy in managing endobronchial lymphoma, even in cases of complete airway occlusion.
- Adds to the limited literature on multiple endobronchial non-Hodgkin's lymphoma, underscoring its rarity and clinical presentation.