Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Amyloid Fibrils

Amyloid Fibrils

Amyloid fibrils are aggregates of misfolded proteins. Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils.
Amyloid deposits were observed as early as 1639 in the liver and the spleen. In 1854, Rudolph Virchow performed iodine staining,...

Amyloid Fibrils

Amyloid Fibrils

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Intraorbital wooden foreign bodies: A retrospective study of 30 cases.

Indian journal of ophthalmology·2026

Same author

Diagnostic Accuracy of a Sonographic Scoring System in Predicting the Malignant Potential of a Soft-tissue Swelling.

Journal of medical ultrasound·2026

Same author

Immunohistochemical Diversity of Endometrial Carcinoma and Their Implications in Prognosis: A Prospective Clinicopathological Study in a Tertiary Care Hospital of Eastern India.

Journal of obstetrics and gynaecology of India·2025

Same author

Unilateral Proptosis as the Initial Manifestation of Acute Myeloid Leukemia in a Young Adult.

Cureus·2024

Same author

Calvarial metastasis from adenocarcinoma of lung: An uncommon initial presentation diagnosed by cytology.

Journal of cancer research and therapeutics·2020

Same author

Closure of sino-orbital fistula using glabellar rotation flap: A case report.

Nepalese journal of ophthalmology : a biannual peer-reviewed academic journal of the Nepal Ophthalmic Society : NEPJOPH·2020

Same journal

Fungal keratitis treatment: Unveiling strategies and emerging trends - A systematic review.

Oman journal of ophthalmology·2026

Same journal

Leber hereditary optic neuropathy triggered by the AstraZeneca coronavirus disease 2019 vaccination.

Oman journal of ophthalmology·2026

Same journal

"Ocular syphilis with reactive arthritis mimicking rheumatoid arthritis" - A diagnostic dilemma, case report, and review of literature.

Oman journal of ophthalmology·2026

Same journal

Spontaneously arrested primary congenital glaucoma.

Oman journal of ophthalmology·2026

Same journal

The impact of the global economic crisis on ophthalmologists in low- to middle-income countries during the COVID-19 pandemic.

Oman journal of ophthalmology·2026

Same journal

Vitreous hemorrhage after weight loss therapy.

Oman journal of ophthalmology·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Apr 30, 2026

A Non-invasive Way to Isolate and Phenotype Cells from the Conjunctiva

A Non-invasive Way to Isolate and Phenotype Cells from the Conjunctiva

Published on: July 5, 2017

Primary conjunctival amyloidosis.

Chandana Chakraborti¹, Krittika P Chaudhury¹, Ranu Roy Biswas¹

¹Department of Ophthalmology, Calcutta National Medical College and Hospital, Kolkata, West Bengal, India.

Oman Journal of Ophthalmology

|May 7, 2014

Summary

This summary is machine-generated.

This case report details a rare instance of isolated primary conjunctival amyloidosis in a young male. Successful treatment involved surgical excision and cryotherapy for this eyelid condition.

Keywords:

Amyloidosis conjunctiva cryotherapy

More Related Videos

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Iris Fixation via External Pentagram Suturing

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

Related Experiment Videos

Last Updated: Apr 30, 2026

A Non-invasive Way to Isolate and Phenotype Cells from the Conjunctiva

A Non-invasive Way to Isolate and Phenotype Cells from the Conjunctiva

Published on: July 5, 2017

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Iris Fixation via External Pentagram Suturing

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

Area of Science:

Ophthalmology
Histopathology

Background:

Conjunctival amyloidosis is a rare condition characterized by amyloid deposition in the conjunctiva.
Primary conjunctival amyloidosis, particularly isolated forms, is exceptionally uncommon.

Observation:

A 19-year-old male presented with a 4-year history of painless right upper eyelid ptosis.
Ocular examination revealed a yellowish-pink mass in the tarsal region of the right upper eyelid.
Initial biopsy indicated chronic inflammation, but subsequent excision and histopathology confirmed subconjunctival amyloid deposition.

Findings:

The patient developed similar lesions in the right lower, left upper, and lower eyelids within 3 months.
These subsequent lesions showed partial resolution following cryotherapy.
The patient remained asymptomatic with no recurrence for over 2 years post-treatment.

Implications:

This is the first reported case of isolated primary conjunctival amyloidosis affecting both upper and lower palpebral conjunctiva in either eye.
Successful management was achieved through a combination of surgical excision and cryotherapy.
Highlights the importance of thorough histopathological examination for diagnosing rare conjunctival masses.