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Gastrointestinal motility disorders in children
Lusine Ambartsumyan1, Leonel Rodriguez1
1Dr Ambartsumyan is the director of the Gastrointestinal Motility Program at Seattle Children's Hospital in Seattle, Washington. Dr Rodriguez is the codirector of the Colorectal Center at the Center for Motility and Functional Gastrointestinal Disorders at Boston Children's Hospital and Harvard Medical School in Boston, Massachusetts.
Insights
Pediatric gastrointestinal motility disorders like GERD and constipation are common and challenging. Better data on diagnosis and treatment is needed for these conditions affecting children.
Area of Science:
- Pediatric Gastroenterology
- Gastrointestinal Motility Disorders
Background:
- Common pediatric gastrointestinal motility disorders include GERD, achalasia, gastroparesis, pseudo-obstruction, and constipation.
- GERD is most common, treated with acid blockers; achalasia involves dysphagia, treated with dilation or myotomy.
- Gastroparesis, pseudo-obstruction, and constipation cause significant morbidity and impact quality of life.
Purpose of the Study:
- To review common pediatric gastrointestinal motility disorders.
- To highlight challenges in diagnosis and treatment.
- To identify needs for improved patient outcomes.
Main Methods:
- Literature review of pediatric gastrointestinal motility disorders.
- Analysis of current diagnostic and treatment approaches.
- Identification of research gaps.
Main Results:
- Gastroesophageal reflux disease (GERD) is the most prevalent.
- Esophageal achalasia, gastroparesis, and chronic intestinal pseudo-obstruction present unique challenges.
- Constipation significantly impacts children's quality of life.
Conclusions:
- Further research is crucial for better diagnosis and treatment of pediatric GI motility disorders.
- Epidemiology, clinical trials, and diagnostic techniques require further investigation.
- Addressing these disorders can improve pediatric health and well-being.
Abstract:
The most common and challenging gastrointestinal motility disorders in children include gastroesophageal reflux disease (GERD), esophageal achalasia, gastroparesis, chronic intestinal pseudo-obstruction, and constipation. GERD is the most common gastrointestinal motility disorder affecting children and is diagnosed clinically and treated primarily with acid secretion blockade. Esophageal achalasia, a less common disorder in the pediatric patient population, is characterized by dysphagia and treated with pneumatic balloon dilation and/or esophagomyotomy. Gastroparesis and chronic intestinal pseudo-obstruction are poorly characterized in children and are associated with significant morbidity. Constipation is among the most common complaints in children and is associated with significant morbidity as well as poor quality of life. Data on epidemiology and outcomes, clinical trials, and evaluation of new diagnostic techniques are needed to better diagnose and treat gastrointestinal motility disorders in children. We present a review of the conditions and challenges related to these common gastrointestinal motility disorders in children.
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