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Crimean Congo hemorrhagic fever in Hazara division

Saqib Malik, Inayat Ullah Diju, Farhat Naz

    Journal of Ayub Medical College, Abbottabad : JAMC
    |May 8, 2014
    PubMed

    Insights

    Crimean-Congo Hemorrhagic Fever (CCHF) is a deadly tick-borne disease in Pakistan. Early evaluation for fever and low platelets is crucial, and oral Ribavirin shows promise for treating CCHF.

    Area of Science:

    • Infectious Diseases
    • Virology
    • Public Health

    Background:

    • Crimean-Congo Hemorrhagic Fever (CCHF) is an endemic, highly fatal zoonotic disease in Pakistan.
    • The study addresses the need for focus on this emerging disease due to numerous outbreaks and sporadic cases.

    Purpose of the Study:

    • To describe the clinical features, treatment, and outcomes of CCHF cases during an outbreak in Hazara division.
    • To highlight the significance of CCHF as a fatal emerging disease.

    Main Methods:

    • Study conducted at Ayub Teaching Hospital, Abbottabad over three months.
    • Included patients with fever and platelet count < 50,000/mm3.
    • CCHF virus detection via blood samples; supportive care with fresh frozen plasma and oral Ribavirin administered.

    Main Results:

    • Eighty-eight patients with fever and thrombocytopenia were analyzed.
    • Eight patients tested positive for CCHF.
    • Six patients recovered fully, one died, and one left against medical advice.

    Conclusions:

    • Suspicion and evaluation for CCHF are recommended for all patients with acute fever and thrombocytopenia.
    • Oral Ribavirin demonstrated safety and effectiveness in CCHF treatment.
    Abstract

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