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Features of severe asthma in young children from Romania
Insights
This study introduces the "Asthma Decalogue in Children" algorithm to identify severe asthma in pediatric patients. The tool effectively distinguishes severe asthma from other reactive airway diseases in children.
Area of Science:
- Pediatric Pulmonology
- Respiratory Medicine
- Clinical Allergy
Background:
- Childhood asthma is a prevalent chronic condition with persistent challenges in achieving control despite advancements.
- Severe asthma is recognized as a heterogeneous condition, often misdiagnosed or broadly categorized.
Purpose of the Study:
- To evaluate the efficacy of a novel algorithm, the "Asthma Decalogue in Children," for diagnosing severe asthma in pediatric patients.
- To differentiate children with true severe asthma from those with other reactive airway diseases presenting as severe.
Main Methods:
- A prospective study involving children referred for severe asthma or recurrent wheezing.
- Application of the "Asthma Decalogue in Children" algorithm in two respiratory clinics.
- Analysis of patient characteristics and diagnostic outcomes for 202 children completing the study.
Main Results:
- Out of 202 children, 49 (22.69%) had severe disease, with only 8 (3.7%) confirmed as severe asthma.
- Children with severe asthma were older, had less male predominance, and exhibited higher rates of rhino-conjunctivitis and Vitamin D deficiency.
- The "Asthma Decalogue in Children" algorithm demonstrated efficiency in differentiating severe asthma.
Conclusions:
- The "Asthma Decalogue in Children" is an effective tool for identifying severe asthma in pediatric populations.
- Accurate differentiation of severe asthma is crucial for appropriate management of childhood respiratory conditions.
Abstract:
Asthma is the most frequent chronic disease of childhood. In spite of significant improvement of treatment options and diagnostic tools, asthma remains in many patients uncontrolled. The term of "severe asthma" seems to be rather a large umbrella for a heterogeneous group of diseases. This paper is presenting our experience in two respiratory disease clinics that evaluate asthmatic children. Current study was designed to test an algorithm for daily practice in a special group of patients: children with previously diagnosed asthma or recurrent-wheezing, evaluated by family physician or pediatrician as severe disease ("Asthma Decalogue in Children"). Out of 313 referrals (during a six months inclusion time) we had 202 children completing study per-protocol. 49 (22.69%) had severe disease, but only 8 had severe asthma (3.7% of total patients and 18.6% of severe patients). They were older, with less male predominance and with more frequent rhino-conjunctivitis and D vitamin deficiency than other asthmatic children with less severe disease. Asthma Decalogue in Children seems to be an efficient tool to differentiate severe asthma from the rest of children with reactive airway diseases.