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Characterization of a Pathogenic Escherichia coli Strain Derived from Oreochromis spp. Farms Using Whole-Genome Sequencing
Published on: December 23, 2022
Complete genome sequencing and comparative analysis of the linezolid-resistant Enterococcus faecalis strain DENG1
Zhijian Yu1, Zhong Chen, Hang Cheng
1Shenzhen Key Lab for Endogenous Infection, Department of Infectious Diseases, The Affiliated Shenzhen Nanshan Hospital, Guangdong Medical College, No 89, Taoyuan Road, Nanshan district, Shenzhen, 518052, China.
Abstract:
Genome level analysis of bacterial strains provides information on genetic composition and resistance mechanisms to clinically relevant antibiotics. To date, whole genome characterization of linezolid-resistant Enterococcus faecalis isolated in the clinic is lacking. In this study, we report the entire genome sequence, genomic characteristics and virulence factors of a pathogenic E. faecalis strain, DENG1. Our results showed considerable differences in genomic characteristics and virulence factors compared with other E. faecalis strains (V583 and OG1RF). The genome of this LZD-resistant E. faecalis strain can be used as a reference to study the mechanism of LZD resistance and the phylogenetic relationship of E. faecalis strains worldwide.
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