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Related Concept Videos

Cholecystitis01:20

Cholecystitis

29
Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...
29
Microbiota of the Stomach and Small Intestine01:27

Microbiota of the Stomach and Small Intestine

77
The human gastrointestinal (GI) tract is characterized by distinct physicochemical conditions that shape its microbial communities. Among these, the stomach presents a particularly challenging environment for microbial colonization due to its highly acidic pH, ranging from 1 to 3. This extreme acidity effectively limits microbial density. However, certain acid-tolerant microorganisms are capable of surviving in this niche. Notably, Helicobacter pylori can colonize the gastric mucosa,...
77
Development of Human Microbiota01:30

Development of Human Microbiota

61
The human microbiota begins developing at birth and undergoes continual change as we age. Infancy marks a critical period of microbial sensitivity, offering a “window of opportunity” during which beneficial microbes help mature the immune system. By age three, children typically develop a more stable and diverse microbial community. Newborns acquire microbes from their immediate environment; vaginal delivery favors maternal vaginal microbes, while cesarean births favor microbes from...
61
Microbiota of the Large Intestine01:27

Microbiota of the Large Intestine

98
The large intestine hosts the most densely populated microbial ecosystem in the human body. This complex community primarily consists of anaerobic bacteria, with Bacillota (formerly Firmicutes) and Bacteroidota (formerly Bacteroidetes) as the predominant groups. The distribution of these microbes varies along different sections of the large intestine, influenced by local environmental factors such as oxygen availability and nutrient composition.The cecum, located at the beginning of the large...
98
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

900
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
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Microbiome of the Eye01:22

Microbiome of the Eye

67
The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...
67

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Related Experiment Video

Updated: Apr 30, 2026

Intraoperative Video Consultation Following Bile Duct Transection Facilitates Direct OR Transfer for Robotic Hepaticojejunostomy at Tertiary Center
07:48

Intraoperative Video Consultation Following Bile Duct Transection Facilitates Direct OR Transfer for Robotic Hepaticojejunostomy at Tertiary Center

Published on: January 9, 2026

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Biliary microflora in patients undergoing cholecystectomy.

Bahman Darkahi1, Gabriel Sandblom, Håkan Liljeholm

  • 11 Department of Surgery, Enköping Hospital , Enköping, Sweden .

Surgical Infections
|May 8, 2014
PubMed
Summary
This summary is machine-generated.

Bacterial growth in bile is more common in acute cholecystitis patients. This biliary microflora impacts surgical outcomes and post-operative infection risk, necessitating further research for prevention strategies.

Related Experiment Videos

Last Updated: Apr 30, 2026

Intraoperative Video Consultation Following Bile Duct Transection Facilitates Direct OR Transfer for Robotic Hepaticojejunostomy at Tertiary Center
07:48

Intraoperative Video Consultation Following Bile Duct Transection Facilitates Direct OR Transfer for Robotic Hepaticojejunostomy at Tertiary Center

Published on: January 9, 2026

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Area of Science:

  • Gastroenterology
  • Surgical Infections
  • Microbiology

Background:

  • Effective management of acute cholecystitis relies on understanding biliary microflora.
  • Biliary tract infections are a significant concern in surgical patient outcomes.

Purpose of the Study:

  • To investigate the prevalence of bacterial growth in bile during cholecystectomies.
  • To determine the association between biliary microflora and acute cholecystitis.
  • To identify risk factors for post-operative infectious complications.

Main Methods:

  • Bile samples were cultured during cholecystectomies performed between April 2007 and February 2009.
  • Data on antibiotic use, surgical indication, and complications were prospectively collected.
  • Multivariable logistic regression analyzed associations between positive cultures and complications.

Main Results:

  • Bacterial growth was detected in 14% of all bile cultures.
  • Positive cultures were significantly more frequent in patients with acute cholecystitis (31%) compared to others (9%).
  • Positive bile culture was the sole significant predictor of post-operative infectious complications.

Conclusions:

  • Bacterial presence in bile is more prevalent in acute cholecystitis cases.
  • Biliary microflora appears crucial for surgical outcomes, influencing post-operative infection risk.
  • Further research is needed to develop effective preventative measures for surgical site infections.