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Improved measurement of intersession latency in mfVEPs
L De Santiago1, A Fernández, R Blanco
1Biomedical Engineering Research Group, Department of Electronics, University of Alcalá, Madrid, Spain.
Purpose:
The purpose of the study is to present a method (Selfcorr) by which to measure intersession latency differences between multifocal VEP (mfVEP) signals.
Methods:
The authors compared the intersession latency difference obtained using a correlation method (Selfcorr) against that obtained using a Template method. While the Template method cross-correlates the subject's signals with a reference database, the Selfcorr method cross-correlates traces across subsequent recordings taken from the same subject.
Results:
The variation in latency between intersession signals was 0.8 ± 13.6 and 0.5 ± 5.0 ms for the Template and Selfcorr methods, respectively, with a coefficient of variability CV_TEMPLATE = 15.83 and CV_SELFCORR = 5.68 (n = 18, p = 0.0002, Wilcoxon). The number of analyzable sectors with the Template and Selfcorr methods was 36.7 ± 8.5 and 45.3 ± 8.7, respectively (p = 0.0001, paired t test, two tailed).
Conclusions:
The Selfcorr method produces smaller intersession mfVEP delays and variability over time than the Template method.
