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IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document...
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Updated: Apr 30, 2026

Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice
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Lupus pernio--a patient case study.

Aadarsh Shah1, Raj Lakhani, Jaan Panesar

  • 1Department of Otolaryngology, Luton and Dunstable University Hospital , Luton, LU4 0DZ , England .

Journal of Visual Communication in Medicine
|May 8, 2014
PubMed
Summary
This summary is machine-generated.

Lupus pernio, a rare skin manifestation of sarcoidosis, can indicate a more aggressive disease. Photography aids in diagnosis and monitoring treatment for this condition.

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Area of Science:

  • Dermatology
  • Internal Medicine
  • Otolaryngology

Background:

  • Sarcoidosis is a multisystem inflammatory disease.
  • Skin manifestations occur in approximately 25% of sarcoidosis patients.
  • Lupus pernio is a specific, less common cutaneous presentation of sarcoidosis.

Observation:

  • An 80-year-old female presented with lupus pernio.
  • The patient's lupus pernio was a visible sign of her underlying sarcoidosis.
  • High-quality photography was utilized for diagnostic purposes.

Findings:

  • Lupus pernio may be associated with a more severe or aggressive form of sarcoidosis.
  • Diagnostic imaging, including photography, is crucial for identifying and tracking sarcoidosis progression.
  • The photographic record served as a vital baseline for evaluating treatment efficacy.

Implications:

  • Early identification of lupus pernio can prompt further investigation for systemic sarcoidosis.
  • Recognizing lupus pernio as a potential marker for aggressive disease aids in treatment planning.
  • Photographic documentation is essential for objective assessment of treatment response in cutaneous sarcoidosis.