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Magnetic-resonance-based electrical properties tomography: a review
IEEE Reviews in Biomedical Engineering
|May 8, 2014
Summary
Electrical properties tomography (EPT) noninvasively images tissue conductivity and permittivity using MRI. This review covers EPT theory, algorithms, and applications in tumor detection and safety assessments.
Area of Science:
- Biophysics
- Medical Imaging
- Electromagnetism
Background:
- Frequency-dependent electrical properties (EPs) of biological tissues are crucial for medical diagnostics, such as tumor characterization.
- Accurate quantification of radiofrequency (RF) coil induced specific absorption rate (SAR) is essential for safety in high-field magnetic resonance imaging (MRI).
Purpose of the Study:
- To review the fundamental theory and recent advancements in electrical properties tomography (EPT).
- To focus on imaging reconstruction methods for EPT, detailing algorithms and validation studies.
- To highlight EPT applications in in vivo tumor detection and subject-specific SAR prediction.
Main Methods:
- Review of electromagnetic theory underpinning EPT.
- Analysis of various EPT imaging reconstruction algorithms.
- Examination of validation studies using physical phantoms and biological tissues.
Main Results:
- EPT enables noninvasive, quantitative reconstruction of electrical property distributions with high spatial resolution.
- Reviewed algorithms demonstrate successful validation in phantoms and tissues.
- EPT shows promise for in vivo tumor detection and personalized SAR estimation.
Conclusions:
- EPT is a powerful technique for mapping tissue electrical properties in MRI.
- Further research is needed to address existing challenges and expand EPT applications.
- EPT contributes significantly to both diagnostic imaging and MRI safety.
