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[Clinicopathological study of pseudomyxoma peritonei]
A Kataoka1, M Yakushiji, T Sugiyama
1Department of Obstetrics and Gynecology, Kurume University School of Medicine.
Nihon Sanka Fujinka Gakkai Zasshi
|November 1, 1989
Summary
Pseudomyxoma peritonei cases were analyzed, revealing that intraperitoneal washing with dextran improved survival rates. This suggests dextran washing is an effective treatment for this rare condition.
Area of Science:
- Oncology
- Gastroenterology
- Pathology
Background:
- Pseudomyxoma peritonei is a rare condition characterized by mucinous ascites.
- Understanding its histogenesis and optimal treatment is crucial for patient outcomes.
Purpose of the Study:
- To clinicopathologically analyze cases of pseudomyxoma peritonei.
- To evaluate the effectiveness of different treatment modalities, including intraperitoneal dextran washing.
Main Methods:
- Clinicopathological analysis of twelve pseudomyxoma peritonei cases.
- Review of patient history, histological findings, cytological examinations, and treatment outcomes.
- Comparison of survival rates based on treatment interventions (surgery alone, surgery with chemotherapy, surgery with chemotherapy and dextran washing).
Main Results:
- Histological diagnoses ranged from benign to frankly malignant.
- Cytological examination identified malignancy in 4 out of 6 cases.
- Intraperitoneal washing with dextran resulted in survival for all three treated cases, though for less than 5 years, suggesting it as a potentially effective therapy.
Conclusions:
- Pseudomyxoma peritonei may be linked to inflammation associated with mucinous tumors.
- Diagnosis should integrate both cytological and radiological assessments.
- Intraperitoneal dextran washing shows promise as an effective treatment for pseudomyxoma peritonei.