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A Triad of Congenital Diaphragmatic Hernia, Meckel's Diverticulum, and Heterotopic Pancreas

Parkash Mandhan1, Amer Al Saied1, Mansour J Ali1

  • 1Department of Pediatric Surgery, Hamad General Hospital, Hamad Medical Corporation, P.O. Box 3050, Doha, Qatar.

Case Reports in Pediatrics
|May 8, 2014
PubMed

Insights

This case report details a rare triad of congenital diaphragmatic hernia, Meckel's diverticulum, and heterotopic pancreatic tissue in a newborn. It explores potential developmental mechanisms for this unique combination of congenital anomalies.

Area of Science:

  • Pediatric Surgery
  • Developmental Biology
  • Gastrointestinal Surgery

Background:

  • Congenital diaphragmatic hernia (CDH) is a significant congenital anomaly affecting newborns.
  • CDH is frequently associated with extradiaphragmatic malformations, including cardiac, renal, genital, and chromosomal abnormalities.

Purpose of the Study:

  • To report the first case of a newborn presenting with the rare triad of CDH, Meckel's diverticulum, and heterotopic pancreatic tissue.
  • To describe the potential developmental mechanisms underlying this specific combination of congenital anomalies.

Main Methods:

  • Case report of a newborn with concurrent congenital diaphragmatic hernia, Meckel's diverticulum, and heterotopic pancreatic tissue.
  • Review of relevant literature to explore potential embryological explanations.

Main Results:

  • A newborn was diagnosed with the simultaneous occurrence of congenital diaphragmatic hernia, Meckel's diverticulum, and heterotopic pancreatic tissue.
  • This represents the first documented instance of this specific triad of congenital malformations.

Conclusions:

  • The co-occurrence of CDH, Meckel's diverticulum, and heterotopic pancreatic tissue is exceptionally rare.
  • Understanding the developmental pathways may offer insights into the pathogenesis of complex congenital anomalies.

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