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Updated: Apr 30, 2026

Development of a Rabbit Chronic-Like Rotator Cuff Injury Model for Study of Fibrosis and Muscular Fatty Degeneration
Published on: March 31, 2023
Factors affecting rotator cuff healing
Nathan A Mall1, Miho J Tanaka1, Luke S Choi1
1Regeneration Orthopedics, 6 McBride and Son Center Drive, Suite 204, St. Louis, MO 63005. E-mail address for N.A. Mall: nathanmall@yahoo.com. E-mail address for L.S. Choi: lukeschoi@gmail.com. E-mail address for G.A. Paletta Jr.: gpaletta@toc-stl.com.
Abstract:
Several studies have noted that increasing age is a significant factor for diminished rotator cuff healing, while biomechanical studies have suggested the reason for this may be an inferior healing environment in older patients. Larger tears and fatty infiltration or atrophy negatively affect rotator cuff healing. Arthroscopic rotator cuff repair, double-row repairs, performing a concomitant acromioplasty, and the use of platelet-rich plasma (PRP) do not demonstrate an improvement in structural healing over mini-open rotator cuff repairs, single-row repairs, not performing an acromioplasty, or not using PRP. There is conflicting evidence to support postoperative rehabilitation protocols using early motion over immobilization following rotator cuff repair.
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