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Conservative management of primary cervical lymphoma using combination chemotherapy: a case report
C Johnston1, E K Senekjian, M J Ratain
1Department of Obstetrics and Gynecology, University of Chicago, Pritzker School of Medicine, Illinois 60637.
Gynecologic Oncology
|December 1, 1989
Abstract:
A 22-year-old nulligravida presented with a stage IE/IIIB primary malignant lymphoma of the cervix which measured 8 cm in diameter. In order to preserve reproductive potential, a 12-week course of methotrexate with leucovorin rescue, doxorubicin, cyclophosphamide, vincristine, prednisone, and bleomycin was administered. One month later a 4-cm-diameter left parametrial mass was excised at laparotomy; no tumor was detected in the specimens obtained. Menses resumed after an additional 6 months. The patient was clinically disease-free at the 33-month follow-up.