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Updated: Apr 30, 2026

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
A new scoring system for upper airway pediatric sleep endoscopy
Dylan K Chan1, Bryan J Liming2, David L Horn3
1Division of Pediatric Otolaryngology, Department of Otolaryngology-Head and Neck Surgery, University of California, San Francisco.
A new scoring system for pediatric drug-induced sleep endoscopy quantifies airway obstruction, showing good reliability and validity. This tool aids in diagnosing sleep-related breathing disorders and planning surgical interventions.
Area of Science:
- Otolaryngology
- Pediatric Sleep Medicine
- Respiratory Medicine
Background:
- Sleep-associated upper-airway obstruction is a significant cause of morbidity in children.
- Standardized, quantitative assessment of airway anatomy is crucial for surgical planning and research in pediatric sleep disorders.
Purpose of the Study:
- To design, implement, and evaluate a scoring system for quantifying airway obstruction during pediatric drug-induced sleep endoscopy (DISE).
Main Methods:
- A retrospective case series of children with sleep-related breathing disorder undergoing polysomnography and DISE.
- Flexible fiber-optic laryngoscopy was performed, with videos assessed by 4 raters using a 4-point scale for obstruction at 5 airway locations.
- Internal reliability (interrater and intrarater ICCs) and external validity (correlation with polysomnography indices) were evaluated.
Main Results:
- The scoring system demonstrated substantial agreement among raters (70% of ICCs > 0.6).
- Higher total obstruction scores correlated with lower oxygen saturation nadir (P = .04).
- Multilevel airway obstruction identified by the system was associated with significantly worse polysomnography indices (P = .02).
Conclusions:
- The proposed scoring system is easy to use, achieves good internal reliability and external validity for quantifying obstruction in pediatric DISE.
- Standardized reporting of DISE outcomes will improve clinical communication and interpretation of findings.
- This system aids in informing site-directed surgical interventions for obstructive sleep apnea in children.
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