Demographic disparities of children presenting with symptomatic Meckel's diverticulum in children's hospitals
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Published on: September 11, 2018
Hanna Alemayehu1, Matt Hall, Amita A Desai
1Section of General Surgery, Department of Surgery, The Children's Mercy Hospital, 2401 Gillham Road, Kansas City, MO, 64108, USA.
Insights
Symptomatic Meckel's diverticulum (MD) is more common in males and White children. This large-scale study analyzed pediatric hospital data to understand MD epidemiology and demographics.
Area of Science:
- Pediatric Surgery
- Epidemiology
- Gastroenterology
Background:
- Existing Meckel's diverticulum (MD) literature primarily comprises single-center case series.
- Large-scale epidemiological data on pediatric Meckel's diverticulum is limited.
Purpose of the Study:
- To investigate the epidemiology of symptomatic Meckel's diverticulum (MD) in a large, geographically diverse pediatric population.
- To identify demographic factors, including age, gender, and race, associated with symptomatic MD in children.
Main Methods:
- Utilized the Pediatric Health Information System (PHIS) database for a 9-year period.
- Included de-identified patients with ICD-9 diagnoses of MD and Meckel's diverticulectomy procedure codes.
- Excluded data from five hospitals due to incomplete information.
Main Results:
- Analyzed 4,338,396 pediatric admissions, identifying 945 cases of symptomatic MD.
- Symptomatic MD incidence decreased with age, with 56.4% of cases in children under 5.
- Males (74%) and Caucasians (63.4%) were significantly over-represented in the symptomatic MD group compared to the general pediatric population.
Conclusions:
- Symptomatic Meckel's diverticulum demonstrates significant gender and racial predilections.
- Males and non-Hispanic White children present more frequently with symptomatic MD.
- Non-Hispanic Black children were less commonly diagnosed with symptomatic MD.
Purpose:
Most of the literature about Meckel's diverticulum (MD) consists of single institutional longitudinal case series. We queried the pediatric hospital information system (PHIS) database to obtain information about the epidemiology of MD from a large number of children at geographically diverse locations.
Methods:
After IRB approval, the PHIS database was queried over a 9-year period for de-identified patients with both ICD-9 diagnoses of MD and a procedure code for Meckel's diverticulectomy. Data from five hospitals were excluded due to incomplete information.
Results:
4,338,396 were children admitted during the study interval; 945 had a symptomatic MD. The incidence decreased with age: 56.4% were under 5 years old, 26.8% were between the ages of 6-12 years, and 16.8% were older than 12 years. 74% were male, which was significantly higher than the PHIS population (53.8% male, P < 0.0001). Caucasians are over-represented in the symptomatic MD group (63.4%) compared to the rest of the PHIS population (48.1%, P < 0.0001).
Conclusions:
According to the PHIS data, there appears to be significant gender and race influence on symptomatic MD. Males present more commonly, as do non-Hispanic White patients, while it is less common among non-Hispanic Black patients.
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