HER2 directed therapy for gastric/esophageal cancers

Elizabeth Won1, Yelena J Janjigian, David H Ilson

  • 1Gastrointestinal Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, 300 East 66th Street, New York, NY, 10065, USA.

Summary

Advanced esophagogastric cancer has a poor prognosis. Trastuzumab shows promise in HER2-positive cases, improving survival, but resistance is a challenge. New therapies are under investigation.

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