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Updated: Apr 30, 2026

Compact Quantum Dots for Single-molecule Imaging
Published on: October 9, 2012
Single-layered graphitic-C(3)N(4) quantum dots for two-photon fluorescence imaging of cellular nucleus
Xiaodong Zhang1, Hongxia Wang, Hui Wang
1Hefei National Laboratory for Physical Sciences at the Microscale, Collaborative Innovation Center of Chemistry for Energy Materials, University of Science and Technology of China, Hefei, Anhui, 230026, P. R. China.
Abstract:
A promising, safe, and economic fluorescent probe, g-C3 N4 single-layered QDs, is introduced for two-photon fluorescence imaging of the cellular nucleus for the first time. The large two-photon absorption cross section, the high photostability, good biocompatibility and non-toxicity, negligible photothermal effect, and specific interaction with DNA render the single-layered g-C3 N4 QDs as a promising candidate for in vivo and in vitro two-photon fluorescence imaging and further biomedical applications.

