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Related Concept Videos

Cardiovascular System Abnormal Findings I: Inspection and Palpation01:29

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Related Experiment Video

Updated: Apr 30, 2026

Diffuse Reflectance Spectroscopy: Getting the Capillary Refill Test Under One's Thumb
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Capillary refill time exploration during septic shock.

H Ait-Oufella1, N Bige, P Y Boelle

  • 1AP-HP, Hôpital Saint-Antoine, Service de Réanimation Médicale, 184 rue du Faubourg Saint-Antoine, 75571, Paris Cedex 12, France, hafid.aitoufella@sat.aphp.fr.

Intensive Care Medicine
|May 10, 2014
PubMed
Summary
This summary is machine-generated.

Capillary refill time (CRT) is a reproducible measure for assessing microvascular perfusion in septic shock patients. Elevated CRT after initial resuscitation strongly predicts 14-day mortality, aiding in prognosis.

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Area of Science:

  • Critical Care Medicine
  • Hemodynamics
  • Microcirculation

Background:

  • Assessing microvascular perfusion is crucial in septic shock management.
  • Skin analysis, specifically capillary refill time (CRT), offers a potential method for this evaluation.

Purpose of the Study:

  • To investigate the reproducibility and prognostic value of skin capillary refill time (CRT) in a septic shock population.
  • To determine if CRT measurements can predict 14-day mortality after initial resuscitation.

Main Methods:

  • A prospective observational study was conducted in a tertiary teaching hospital.
  • Capillary refill time (CRT) was measured on the index finger tip and knee area after initial resuscitation at 6 hours (H6).
  • Hemodynamic parameters were recorded, and their predictive value for 14-day mortality was analyzed.

Main Results:

  • CRT measurements demonstrated high reproducibility between raters.
  • Patients with higher CRT values at H6 had significantly increased 14-day mortality.
  • CRT at H6 was a strong predictor of 14-day mortality, with specific thresholds identified for index (2.4s) and knee (4.9s) measurements.
  • CRT correlated with tissue perfusion markers like arterial lactate and SOFA score.

Conclusions:

  • Capillary refill time (CRT) is a reproducible clinical parameter for assessing microvascular perfusion in septic shock.
  • CRT measured after initial resuscitation is a significant predictor of 14-day mortality in septic shock patients.