Polymerase I and transcript release factor (PTRF) regulates adipocyte differentiation and determines adipose tissue

Sergio Perez-Diaz1, Lance A Johnson2, Robert M DeKroon3

  • 1Adipocyte and Fat Biology Laboratory (AdipoFat), Unidad de Investigación Traslacional, Instituto Aragonés de Ciencias de la Salud (IACS), Hospital Universitario Miguel Servet, Zaragoza, Spain;

Summary

Polymerase I and transcript release factor (PTRF) limits adipose tissue expansion, impacting glucose tolerance and metabolic syndrome. PTRF may serve as a marker for pathological obesity and guide clinical management.

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