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GEPdb: a database for investigating the ternary association of genotype, gene expression and phenotype
Daeun Ryu1, SeongBeom Cho2, Hun Kim1
1Ewha Research Center for Systems Biology (ERCSB), Ewha Womans University, Seoul 120-750, Division of Biomedical Informatics, National Institute of Health, Korea Center for Disease Control, Cheongwon 363-951 and Ewha Global Top5 Research Program, Ewha Womans University, Seoul 120-750, Republic of Korea.
Unlabelled:
GEPdb integrates both genome-wide association studies and expression quantitative trait loci information, the two primary sources of genome-wide mapping for genotype-phenotype and genotype-expression associations together with phenotype-associated gene lists. The GEPdb provides simultaneous interpretation of both genetic risks and potential gene regulatory pathways toward phenotypic outcome by establishing the ternary relationship of genotype-expression-phenotype (GEP). The analytic scope is further extended by linkage disequilibrium from five different populations of the international HapMap Project.
Availability And Implementation:
http://ercsbweb.ewha.ac.kr/gepdb.
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