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Substance P-like immunoreactivity in the gracile nucleus and fasciculus in old mice
K Yamazaki1, H Moriya, T Wakabayashi
1National Institute of Neuroscience, NCNP, Tokyo, Japan.
Neuroscience Letters
|December 4, 1989
Abstract:
Substance P-like immunoreactivity (SPI) was observed in many axonal profiles within the gracile nucleus and fasciculus of 13-month-old mice. No SPI, however, was detected in the gracile nucleus and fasciculus in 3- and 6-month-old mice. The results suggest that the accumulation of SPI elements in axons of the gracile nucleus and fasciculus is one of the age-related changes in the central nervous system.