Impulsivity in remitted depression: a meta-analytical review

Area of Science:

• Psychiatry
• Psychology
• Neuroscience

Background:

• Depressive disorder is frequently associated with impulsivity and suicidal behaviors.
• Understanding trait impulsivity in individuals with a history of depressive disorder is crucial for effective treatment and relapse prevention.

Purpose of the Study:

• To systematically review and synthesize findings on trait impulsivity assessment in individuals with remitted depressive disorder.
• To identify commonly used and validated measures for assessing trait impulsivity in this population.

Main Methods:

• A comprehensive literature search was conducted on Medline, EMBASE, and Psychinfo using keywords related to impulsivity and depression.
• Studies published between 1990 and 2012, reporting impulsivity scores using validated measures in remitted depressive disorder, were included.
• Nine studies met the inclusion criteria and were independently reviewed. Pooled data analysis was performed using Cochrane methodology to calculate weighted mean differences (WMDs).

Main Results:

• The Barratt Impulsivity Scale (BIS) 11 was the most frequently utilized instrument for assessing impulsivity in studies of depressive disorder.
• Analysis of the 9 included studies revealed a significant weighted mean difference (WMD) of 10.12 on the BIS 11 total scores, indicating higher impulsivity in individuals with a history of depression.

Conclusions:

• A robust association exists between trait impulsivity and depressive disorder.
• This association appears to persist even during periods of remission from depressive disorder, suggesting impulsivity as a potential transdiagnostic vulnerability factor.