Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Jan 11, 2026

Bone Marrow Sampling and Transplants

Bone Marrow Sampling and Transplants

From connections to function: the mouse brain connectome atlas.

Olaf Sporns¹, Edward T Bullmore²

¹Department of Psychological and Brain Sciences, Indiana University, Bloomington, IN 47405, USA.

|May 13, 2014

Summary

Researchers mapped the entire mouse brain's wiring, detailing neuronal connections and projections. This provides new insights into brain network organization and function.

Related Concept Videos

Bone Marrow Sampling and Transplants

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Cortical similarity networks in the rat brain: Postnatal development and sensitivity to early life stress.

Network neuroscience (Cambridge, Mass.)·2026

Same author

Peripheral inflammation is associated with reduced influx of TSPO PET tracers into the brain: insights from a non-invasive mapping methodology.

Brain, behavior, and immunity·2026

Same author

Network-based disease fingerprinting with neuroinflammation PET imaging.

Journal of neuroinflammation·2026

Same author

Genetic insights on the mechanisms of human cortical folding.

bioRxiv : the preprint server for biology·2026

Same author

Peripheral Expression of Dopamine Genes as a Biomarker for Cocaine Addiction in Humans.

European addiction research·2026

Same author

Corrigendum to "Acute effects of interferon-alpha on cellular anabolic and catabolic processes are associated with the development of fatigue during Interferon-alpha-based therapy for Hepatitis-C: A preliminary study" [Brain Behav. Immun. 123 (2025) 717-724].

Brain, behavior, and immunity·2026

Area of Science:

Neuroscience
Connectomics
Systems Biology

Background:

Understanding brain dynamics necessitates mapping synaptic connections and projections.
The intricate network organization of neuronal connectivity remains a complex area of study.

Purpose of the Study:

To present a comprehensive wiring diagram of the whole mouse brain.
To reveal new details in the network organization of neuronal connectivity.

Main Methods:

Utilizing standardized labeling techniques for neuronal tracing.
Employing advanced imaging methods for axonal connection analysis.
Developing a whole-brain wiring map.

Main Results:

A detailed wiring diagram of the entire mouse brain was generated.

Related Experiment Videos

Last Updated: Jan 11, 2026

Bone Marrow Sampling and Transplants

Bone Marrow Sampling and Transplants

New insights into the network organization of axonal connections were uncovered.

Standardized methods facilitated comprehensive mapping of neuronal connectivity.

Conclusions:

The study provides a foundational resource for understanding mouse brain organization.
The revealed details enhance our comprehension of brain dynamics and function.
This work advances the field of connectomics through detailed mapping.