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Updated: Apr 30, 2026

Examination of Anatomical Features of Retinal Ganglion Cells Under N-methyl-D-aspartic Acid (NMDA)-induced Excitotoxicity
Published on: September 19, 2025
A recently-discovered NMDA receptor gene, GRIN3B, is associated with duration mismatch negativity
Yi-Ting Lin1, Ming H Hsieh2, Chen-Chung Liu3
1Institute of Biomedical Engineering, National Taiwan University, No. 1, Sec. 1, Jen-Ai Road, Taipei City, Taiwan; Department of Psychiatry, National Taiwan University Hospital and College of Medicine, National Taiwan University, No. 1, Changde Street, Taipei City, Taiwan.
Abstract:
The study explored associations between mismatch negativity and N-methyl-d-aspartic acid receptor subunit genes, GRIN1, GRIN2B and GRIN3B in healthy subjects and schizophrenia. Nineteen single-nucleotide polymorphisms were genotyped in 138 schizophrenia patients and 103 healthy subjects. Rs2240158 of GRIN3B was significantly associated with mismatch negativity in healthy subjects.
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