Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Leukocyte filtration].

N Müller1

  • 1Institut für Transfusionsmedizin, Universitätskliniken Münster, BRD.

Beitrage Zur Infusionstherapie = Contributions to Infusion Therapy
|January 1, 1989
PubMed
Summary
This summary is machine-generated.

New filters effectively remove over 95% of white blood cells (leukocytes) from blood products. This significantly reduces transfusion risks like febrile reactions and alloimmunization, preserving platelet quality.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Metabolic control and hypoglycaemia in people with type 2 diabetes on conventional or intensified insulin therapy: a 22 year retrospective single centre survey.

Diabetes/metabolism research and reviews·2016
Same author

Long-term Outcomes in Steroid-refractory Ulcerative Colitis Treated with Tacrolimus Alone or in Combination with Purine Analogues.

Journal of Crohn's & colitis·2015
Same author

HIV-1 Transmission During Recent Infection and During Treatment Interruptions as Major Drivers of New Infections in the Swiss HIV Cohort Study.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2015
Same author

Strong Impact of Smoking on Multimorbidity and Cardiovascular Risk Among Human Immunodeficiency Virus-Infected Individuals in Comparison With the General Population.

Open forum infectious diseases·2015
Same author

The cytoskeletal protein LASP-1 differentially regulates migratory activities of choriocarcinoma cells.

Archives of gynecology and obstetrics·2015
Same author

Increases in Condomless Sex in the Swiss HIV Cohort Study.

Open forum infectious diseases·2015
Same journal

[Not Available].

Beitrage zur Infusionstherapie = Contributions to infusion therapy·1993
Same journal

[Preliminary results of the 2nd multicenter study. Thrombocytapheresis with the Fresenius AS-104 blood cell separator and ring study of cell counting. Section of Therapeutic and Preparative Hemapheresis of the DGTI].

Beitrage zur Infusionstherapie = Contributions to infusion therapy·1993
Same journal

[Thrombocyte substitution in hematologic patients].

Beitrage zur Infusionstherapie = Contributions to infusion therapy·1993
Same journal

[Substitution of thrombocyte concentrates in polytransfused patients].

Beitrage zur Infusionstherapie = Contributions to infusion therapy·1993
Same journal

[Indications for fresh frozen plasma: evaluation of virus inactivating preparations].

Beitrage zur Infusionstherapie = Contributions to infusion therapy·1993
Same journal

[Indications for irradiated blood components: dose and side effects].

Beitrage zur Infusionstherapie = Contributions to infusion therapy·1993
See all related articles

Area of Science:

  • Biomedical Engineering
  • Hematology
  • Transfusion Medicine

Context:

  • Adverse clinical effects of leukocytes in transfusions are increasingly recognized.
  • Leukocyte reduction is crucial for mitigating transfusion-related risks.
  • Existing filtration methods have limitations in efficiency and platelet preservation.

Purpose:

  • To evaluate the efficacy of novel polymer-coated fiber filters for selective white cell removal.
  • To assess the impact of these filters on platelet recovery, morphology, and function.
  • To determine the potential of these filters in reducing transfusion complications.

Summary:

  • New filters utilizing polymer-coated fibers demonstrate high efficiency in removing over 95% of leukocytes from blood products.

Related Experiment Videos

  • These filters minimize platelet loss and maintain normal platelet morphology and in vitro function.
  • Filtration is effective in both bag-to-bag and bedside applications.

    • Impact:

    • Significantly reduces the risk of febrile non-hemolytic transfusion reactions.
    • Aims to lower the threshold for alloimmunization in transfusion recipients.
    • Enhances the safety and efficacy of red cell and platelet transfusions by minimizing white cell-associated adverse events.