Related Experiment Videos
[The first clinical experience with cryopreserved erythrocyte concentrate]
S Pfefferkorn1, A Schleusner, C Raderecht
1Spezialabteilung Hämatologie, Bezirksinstitut für Blutspende-und Transfusionswesen Berlin.
Folia Haematologica (Leipzig, Germany : 1928)
|January 1, 1989
Summary
Frozen stored erythrocyte concentrate (GK-EK) is manufactured and assessed for compatibility and transfusion success. Clinical and laboratory data confirmed no febrile transfusion responses, supporting its use.
Area of Science:
- Hematology
- Transfusion Medicine
- Cryopreservation
Context:
- Erythrocyte concentrate preservation is crucial for blood banking.
- Frozen storage offers extended shelf-life compared to refrigerated methods.
- Evaluating novel preservation techniques like GK-EK is essential for transfusion efficacy.
Purpose:
- To describe the manufacturing process of frozen stored erythrocyte concentrate (GK-EK).
- To assess the clinical compatibility and transfusion success of GK-EK.
- To determine the safety profile, specifically regarding febrile transfusion reactions.
Summary:
- The manufacturing procedure for GK-EK was detailed.
- Clinical and laboratory-chemical parameters were used to evaluate GK-EK compatibility and transfusion success.
- No febrile transfusion responses were observed during the assessment.
Impact:
- GK-EK demonstrates successful compatibility and transfusion efficacy.
- The absence of febrile transfusion responses indicates a favorable safety profile for GK-EK.
- Established indications for the use of GK-EK in clinical practice can be provided.