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Updated: Apr 30, 2026

In Vivo Wireless Optogenetic Control of Skilled Motor Behavior
Published on: November 22, 2021
Working together: basal ganglia pathways in action selection
Danielle M Friend1, Alexxai V Kravitz2
1National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, USA.
Abstract:
Jin, Tecuapetla, and Costa combined in vivo electrophysiology with optogenetic-identification to examine firing in multiple basal ganglia nuclei during rapid motor sequences. Their results support a model of basal ganglia function in which co-activation of the direct and indirect pathways facilitate appropriate, while inhibiting competing, motor programs.
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