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Corrigendum to "Revisiting subcallosal cingulate deep brain stimulation for depression: Long-term safety and effectiveness outcomes from a pooled analysis of 172 implanted patients" [Brain Stimul 18 (2025) 1632-1640].

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Updated: Apr 30, 2026

Non-Invasive Electrical Brain Stimulation Montages for Modulation of Human Motor Function
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Deep brain and motor cortex stimulation.

Vishad V Sukul1, Konstantin V Slavin

  • 1Department of Neurosurgery, Temple University, Philadelphia, PA, 19140, USA, sukulvi@gmail.com.

Current Pain and Headache Reports
|May 13, 2014
PubMed
Summary
This summary is machine-generated.

Deep brain stimulation (DBS) and motor cortex stimulation (MCS) offer advanced neuromodulation for chronic pain refractory to other treatments. Further research and data are needed for regulatory approval and optimized patient selection.

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Area of Science:

  • Neurosurgery
  • Pain Management
  • Neuromodulation

Background:

  • Deep brain stimulation (DBS) and motor cortex stimulation (MCS) are established surgical treatments for chronic pain.
  • These interventions are typically reserved for severe, refractory cases unresponsive to less invasive methods.

Purpose of the Study:

  • To review current understanding and clinical data on DBS and MCS for chronic pain.
  • To identify needs for regulatory approval and future research directions.

Main Methods:

  • Review of worldwide published clinical studies and laboratory reports on DBS and MCS for pain.
  • Analysis of stimulation details, parameters, targets, indications, and outcomes.

Main Results:

  • DBS and MCS appear to modulate central pain processing and descending pain inhibition through multifactorial mechanisms.
  • Current data suggests a need for more evidence to support regulatory approval for pain treatment.

Conclusions:

  • Additional clinical data is required for regulatory approval of DBS and MCS for pain management.
  • Future research should focus on refining patient and procedure selection paradigms post-approval.