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Updated: Apr 30, 2026

A New Murine Model of Endovascular Aortic Aneurysm Repair
Published on: July 7, 2013
Aneurysm formation and infection in AV prosthesis
Miltos K Lazarides1, George S Georgiadis, Christos Argyriou
1Department of Vascular Surgery, Democritus University, Alexandroupolis - Greece.
Aneurysms in prosthetic arteriovenous (AV) grafts are typically false aneurysms, unlike true aneurysms in AV fistulae. Surgical repair is indicated for specific complications, with conventional surgery remaining the standard treatment.
Area of Science:
- Vascular Surgery
- Interventional Radiology
Background:
- True aneurysms are common in autogenous arteriovenous (AV) fistulae.
- False aneurysms are the predominant type in prosthetic AV grafts, followed by anastomotic aneurysms.
Purpose of the Study:
- To outline the indications for repairing aneurysms in prosthetic AV grafts.
- To describe the management options for these aneurysms.
Main Methods:
- Review of current literature and clinical practice regarding prosthetic AV graft aneurysms.
- Discussion of conventional surgical and endovascular techniques for aneurysm management.
Main Results:
- Indications for repair include false aneurysms >2x graft diameter, rapid enlargement, skin erosion, rupture, pain, limited cannulation, and infection.
- Conventional surgery involves resection with in situ interposition graft or resection/exclusion with bypass.
- Endovascular techniques offer an alternative management strategy.
Conclusions:
- Prosthetic AV graft aneurysms, primarily false aneurysms, require repair based on specific clinical criteria.
- Conventional surgery is the established standard, but endovascular options are also considered.
- Surgical approaches aim to address the aneurysm while managing potential contamination risks.
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