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Mg2+ effects on a circle opening reaction of the self-splicing intervening sequence from Tetrahymena thermophila
N Sugimoto1, M Sasaki, R Kierzek
1Department of Chemistry, Faculty of Science, Konan University, Kobe, Japan.
Nucleic Acids Symposium Series
|January 1, 1989
Abstract:
The Mg2+ contribution to the reaction of circular intervening sequence (CIVS) from rRNA precursor of Tetrahymena thermophila with a dinucleotide CU has been investigated. The results indicated that the circle opening of CIVS may involve binding of a weakly held Mg2+ ion.