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Updated: Apr 30, 2026

Bridging the Bio-Electronic Interface with Biofabrication

Bridging the Bio-Electronic Interface with Biofabrication

Published on: June 6, 2012

Engineered proteins for bioelectrochemistry.

Muhammad Safwan Akram¹, Jawad Ur Rehman, Elizabeth A H Hall

¹Institute of Biotechnology, Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge CB2 1QT United Kingdom;

Annual Review of Analytical Chemistry (Palo Alto, Calif.)

|May 14, 2014

Summary

This summary is machine-generated.

Synthetic enzymes and novel electrode interfaces are emerging due to advances in protein engineering and materials science. This enables a new era of bioelectrochemistry by controlling protein structure and electron transfer.

Keywords:

bioelectrochemistry electron transfer protein electrochemistry protein engineering

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Area of Science:

Bioelectrochemistry
Protein Engineering
Materials Science

Background:

Recent advances in protein engineering, materials chemistry, nanofabrication, and electronics have enabled new possibilities.
These advancements facilitate the creation of synthetic enzymes and novel electrode interfaces.

Purpose of the Study:

To review the principles of electron transfer (ET).
To explore how ET at the electrode, within proteins, and at redox groups drives progress in bioelectrochemistry.
To understand protein structure for enhanced efficiency and unique bioelectrochemical systems.

Main Methods:

Review of electron transfer (ET) principles.
Analysis of ET applications at electrode-protein interfaces.
Examination of ET within protein structures and redox groups.

Main Results:

Emergence of synthetic enzymes previously not possible.
Development of novel interfaces with advanced electrode materials.
Demonstration of control over protein structure, electron transport pathways, and electrode surfaces.

Conclusions:

Control over protein structure and electron transport pathways heralds a new era in bioelectrochemistry.
Understanding ET is key to creating efficient and unique bioelectrochemical systems.
The integration of protein engineering and materials science is crucial for future advancements.