Related Experiment Video

Updated: Apr 30, 2026

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
10:46

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

Published on: December 9, 2015

10.3K

Association between serum 25-hydroxyvitamin D levels and TTN

Capan Konca1, Zelal Kahramaner, Mehmet Bulbul

  • 1Department of Pediatrics, Neonatology Clinic, Adiyaman University, School of Medicine, Adiyaman, Turkey.

Hormone Research in Paediatrics
|May 14, 2014
PubMed

Insights

Lower serum 25-hydroxyvitamin D (25(OH)D3) levels are linked to an increased risk of transient tachypnea of the newborn (TTN). Vitamin D may play a role in TTN development.

Area of Science:

  • Neonatal Medicine
  • Pediatric Pulmonology
  • Endocrinology

Background:

  • Transient tachypnea of the newborn (TTN) is a common respiratory disorder in neonates.
  • Vitamin D deficiency is prevalent globally and has been implicated in various health outcomes.

Purpose of the Study:

  • To examine the relationship between serum 25-hydroxyvitamin D (25(OH)D3) levels and the incidence of TTN.
  • To explore potential roles of vitamin D in the pathophysiology of TTN.

Main Methods:

  • Serum levels of 25(OH)D3, calcium, phosphorus, alkaline phosphatase, and parathormone were measured in infants with TTN and healthy controls.
  • Demographic data and details on vitamin D supplementation during pregnancy were collected.

Main Results:

  • Infants with TTN exhibited significantly lower serum 25(OH)D3 levels compared to controls.
  • Elevated parathormone levels were observed in the TTN group, with no significant differences in calcium, phosphorus, or alkaline phosphatase.
  • Maternal vitamin D supplementation did not influence neonatal serum 25(OH)D3 levels.

Conclusions:

  • Lower serum 25(OH)D3 levels are associated with an increased risk of TTN.
  • Findings suggest a potential role for vitamin D in the pathogenesis of TTN.
Abstract

More Related Videos

Genetic Analysis of Hereditary Transthyretin Ala97Ser Related Amyloidosis06:33

Genetic Analysis of Hereditary Transthyretin Ala97Ser Related Amyloidosis

Published on: June 9, 2018

7.2K
A Quantitative Assay to Study Protein:DNA Interactions, Discover Transcriptional Regulators of Gene Expression, and Identify Novel Anti-tumor Agents06:43

A Quantitative Assay to Study Protein:DNA Interactions, Discover Transcriptional Regulators of Gene Expression, and Identify Novel Anti-tumor Agents

Published on: August 31, 2013

17.5K

Related Concept Videos

Translation01:31

Translation

Lesson: Translation
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of...
133.5K
Translation01:31

Translation

Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of Life
Proteins are...
16.8K
Role of Skin in Vitamin D Synthesis01:23

Role of Skin in Vitamin D Synthesis

The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
8.1K
Connective Tissue Cell Types01:22

Connective Tissue Cell Types

Connective tissue develops from the mesoderm of a developing embryo and consists of cells, fibers, and ground substance: a gel-like material containing large complexes of carbohydrates and proteins. Connective tissue was first identified as a separate tissue family in the 18th century, and Johannes Peter Muller coined the term connective tissue.
Fat cells (adipocytes), smooth muscle cells (myoblasts), and bone cells (osteoblasts) are some connective tissue cell types. Some immune system cells...
3.4K
Therapeutic Drug Monitoring: Affecting Factors01:29

Therapeutic Drug Monitoring: Affecting Factors

Therapeutic Drug Monitoring (TDM) is the clinical practice of measuring specific drug levels in a patient's blood or body tissues to manage and optimize therapy. TDM is crucial for drugs with narrow therapeutic windows, like warfarin and phenytoin, where incorrect doses can lead to treatment failure or severe side effects. This monitoring ensures the dosage administered is within a safe and effective range. The factors affecting therapeutic drug monitoring include:Patient-Specific Factors:a.
429
Pharmacogenetics of Drug Targets: β₂-Adrenergic Receptors, Apo E, Thymidylate Synthase01:11

Pharmacogenetics of Drug Targets: β₂-Adrenergic Receptors, Apo E, Thymidylate Synthase

Genetic polymorphisms in drug targets have emerged as critical determinants of interindividual variability in drug response and toxicity. Pharmacogenomic investigations increasingly focus on identifying these variations to personalize and optimize therapeutic interventions. A drug target may be a receptor, enzyme, or signaling protein involved in pharmacologic responses or disease-related pathways. While early pharmacogenetic studies focused primarily on drug metabolism, current research...
81