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Bacteremia caused by an Acinetobacter junii strain harboring class 1 integron and diverse DNA mobile elements

German Matías Traglia1, Marisa Almuzara, Elisabet Vilacoba

  • 1Facultad de Medicina, Universidad de Buenos Aires, Argentina. gertra13a@gmail.com.

Journal of Infection in Developing Countries
|May 14, 2014
PubMed
Abstract

Insights

Molecular characterization of Acinetobacter junii revealed genomic plasticity, explaining its adaptation to hospital environments. This rare bacterial pathogen harbors mobile elements, contributing to antimicrobial resistance acquisition.

Area of Science:

  • Microbiology
  • Genomics

Background:

  • Acinetobacter junii infections are infrequently documented, with prior reports including neonatal septicemia, pediatric oncology infections, meningitis, peritonitis, and ocular infections.
  • Molecular characterization of Acinetobacter junii strains is notably scarce in scientific literature.

Observation:

  • This study details the molecular characterization of Acinetobacter junii isolates obtained from the blood of a renal transplant patient.
  • The patient experienced catheter-related bacteremia caused by Acinetobacter junii and showed a positive response to ciprofloxacin treatment and catheter removal.

Findings:

  • Complete molecular characterization identified a class 1 integron within the Acinetobacter junii isolate.
  • The presence of diverse DNA mobile elements was confirmed, indicating significant genomic plasticity.

Implications:

  • The genomic features identified in this Acinetobacter junii isolate provide insights into its capacity for acquiring antimicrobial resistance.
  • Understanding these mechanisms is crucial for managing nosocomial infections caused by this opportunistic pathogen.

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