Reversible splenial lesion in auto-immune thyroid disease: a case report

Area of Science:

• Neurology
• Endocrinology
• Radiology

Background:

• Reversible splenium of the corpus callosum lesions are a known clinicoradiological syndrome.
• This syndrome is associated with various underlying medical conditions.

Observation:

• A 47-year-old man presented with encephalopathy.
• The patient had associated autoimmune thyroid disease.

Findings:

• A reversible splenial lesion was isolated in the patient.
• This represents a rare radiological finding in autoimmune thyroid disease-associated encephalopathy.

Implications:

• This case expands the spectrum of radiological findings in autoimmune thyroid disease.
• It underscores the importance of considering autoimmune thyroid disease in patients with reversible splenial lesions and encephalopathy.