Immobilization hypercalcemia associated with multiple trauma

This entity is an infrequently reported phenomena, because its manifestations are nonspecific and protean. Three young patients are described who developed hypercalcemia during immobilization following multiple injuries including femoral fractures. This syndrome presented itself with symptoms of continuous anorexia and nausea. Gastrointestinal symptoms occurred within two weeks of immobilization, but the diagnosis was not made for a month. They were treated for hypercalcemia by a decrease in calcium intake, saline infusion, phosphates and mobilization when possible. As the serum calcium levels reached normal limits, the symptoms of anorexia and nausea were alleviated. Mobilization was the definitive treatment for their immobilization hypercalcemia. The protean manifestations of hypercalcemia must be emphasized. When they occur in patients with multiple trauma, hypercalcemia must be evaluated and treated.