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Updated: Apr 29, 2026

An Intramedullary Locking Nail for Standardized Fixation of Femur Osteotomies to Analyze Normal and Defective Bone Healing in Mice
Published on: November 13, 2016
Closed flexible intramedullary fixation for pathologic lesions in long bones
Abstract:
Nine patients with 11 extremities involved with neoplastic metastases were treated with flexible intramedullary rods for stabilization and pain relief. Seven of the nine patients had sustained a fracture, and two patients received prophylactic flexible intramedullary rods for impending fracture. Good pain relief and satisfactory stabilization were accomplished in all but one patient. Methyl methacrylate was not used, and all lesions were treated closed, save for one patient who received good initial pain relief and satisfactory stability but ultimately had tumor recurrence, infection, and loss of fixation. We feel this technique is especially valuable in treating the very ill and terminal patient who might otherwise not tolerate prolonged anesthesia or extensive operative procedures.
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