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Longitudinal stability of specific barriers to medication adherence

Jennifer L Lee1, Cyd Eaton2, Ana M Gutiérrez-Colina2

  • 1Department of Psychology, University of Georgia, Department of Medicine, Division of Population Sciences, Rutgers Cancer Institute of New Jersey, Center for Pain and the Brain, Children's Hospital Boston/Harvard Medical School, and Department of Psychiatry and Behavioral Sciences, Children's Healthcare of Atlanta, Transplant Services/Emory University School of Medicine jenlee09@gmail.com.

Journal of Pediatric Psychology
|May 15, 2014
PubMed

Insights

Specific barriers to medication adherence in pediatric transplant patients remain stable over 18 months. These challenges likely persist without targeted interventions, impacting long-term health outcomes.

Area of Science:

  • Pediatric Transplant Medicine
  • Adherence Research
  • Health Psychology

Background:

  • Barriers to medication adherence negatively impact pediatric transplant recipients' outcomes.
  • While total barriers may be stable, specific barriers require further investigation over time.

Purpose of the Study:

  • To examine the frequency and stability of specific medication adherence barriers in pediatric transplant recipients over 18 months.

Main Methods:

  • 63 parents and 51 adolescents/young adults from kidney, liver, heart, and lung transplant cohorts participated.
  • Perceived barriers to adherence were assessed at two time points, 18 months apart.

Main Results:

  • Most parent- and adolescent-reported specific barriers demonstrated stability between the two assessment periods.
  • Few specific barriers showed significant changes in endorsement levels over the 18-month study duration.

Conclusions:

  • Specific barriers to medication adherence in pediatric transplant patients are generally stable over time.
  • Interventions are likely necessary to modify these persistent barriers and improve patient outcomes.
Abstract

Keywords:
adherenceadolescentsbarrierspediatrictransplantation

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