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Adverse events of targeted therapies

Jean A Klastersky1

  • 1Institut Jules Bordet, Centre des Tumeurs de l'Université Libre de Bruxelles, Brussels, Belgium.

Current Opinion in Oncology
|May 15, 2014
PubMed
Abstract

Insights

The rapid increase in targeted therapies leads to new side effects. Awareness of these adverse events is crucial for improving patient quality of life and recognizing new syndromes.

Area of Science:

  • Oncology
  • Pharmacology

Background:

  • The field of targeted therapies is rapidly expanding.
  • New indications for these agents are continuously emerging.

Purpose of the Study:

  • To review the evolving landscape of targeted therapies and their associated adverse events.
  • To highlight the need for continuous re-evaluation of literature in this dynamic field.

Main Methods:

  • Literature review and synthesis of current data on targeted therapies.
  • Analysis of reported side effects and adverse events associated with these treatments.

Main Results:

  • Targeted therapies are linked to a broad range of adverse events.
  • Differentiating these side effects from cancer complications can be challenging.

Conclusions:

  • High awareness of adverse events from targeted therapies is essential.
  • Recognizing these events can improve patient quality of life and identify new clinical syndromes.

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