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Initial oxygen saturation values can predict the need to hospitalise children with mild wheezing
H Pruikkonen1, M Uhari, T Dunder
1Department of Paediatrics, University of Oulu, University Hospital of Oulu, Oulu, Finland.
Insights
An initial oxygen saturation above 93% in children with acute wheezing indicates a mild condition. This finding could significantly reduce paediatric hospital admissions for respiratory infections.
Area of Science:
- Pediatric Respiratory Medicine
- Emergency Medicine
Background:
- Acute wheezing is a frequent reason for pediatric hospital admissions.
- Identifying predictors of mild disease course is crucial for optimizing resource allocation.
Purpose of the Study:
- To identify factors predicting mild wheezing in children over six months of age.
- To evaluate the utility of initial oxygen saturation in predicting disease severity.
Main Methods:
- Retrospective review of 539 children (6 months-16 years) presenting with wheezing during respiratory infection.
- Disease severity classified by hospital stay duration or intensive care unit admission.
- Analysis of initial oxygen saturation (SaO2) values, with a focus on values below 90%.
Main Results:
- 87% of patients experienced mild disease; 6% had severe disease.
- An initial SaO2 >93% demonstrated a high negative predictive value (93%) for mild disease.
- Applying an SaO2 cutoff of ≤93% could have reduced hospital admissions by nearly 50%.
Conclusions:
- Initial oxygen saturation >93% is a strong indicator of a mild course in acute pediatric wheezing.
- Implementing this SaO2 threshold could significantly decrease unnecessary hospitalizations.
- This simple measure can aid in more efficient management of pediatric respiratory infections.
Aim:
Mild wheezing during respiratory infections is a common cause of paediatric hospital admissions. This study aimed to identify factors predicting this condition in children over six months of age.
Methods:
We reviewed the medical records of 539 children, aged 6 months to 16 years, who visited the emergency department because of wheezing during respiratory infection. Mild disease was defined as hospital stays of less than 48 h and severe disease was staying at least 48 h or being treated in intensive care. Patients with an initial oxygen saturation value (SaO2 ) below 90% were analysed separately.
Results:
Most (87%) of the 539 patients had mild disease, 6% had a severe disease and 7% had an initial SaO2 below 90%. The area under the receiver operating characteristic (ROC) curve for the initial SaO2 predicting mild disease was 0.75 (95% CI 0.53-0.97), and the optimal cut-off value was 93%. An initial SaO2 >93% had a negative predictive value of 93%. Although 270 patients (50%) were hospitalised, only 140 (26%) would have been admitted using an optimal cut-off of SaO2 ≤93%.
Conclusion:
An initial SaO2 >93% reflects a mild course of acute wheezing and using this cut-off point could have almost halved hospital admissions.
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