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Published on: June 18, 2021
Infectious endocarditis presenting as intracranial hemorrhage in a patient admitted for lumbar radiculopathy
David Ethan Kahn1, Kristine O'Phelan1, Ross Bullock2
1Miller School of Medicine University of Miami, Department of Neurology, Clinical Research Building, 1120 NW 14th Street, 13th Floor, Miami, FL 33136, USA.
Insights
Bacterial endocarditis can cause brain hemorrhage, often due to mycotic aneurysms. Prompt diagnosis via imaging and cultures is crucial for identifying this rare but serious complication.
Area of Science:
- Neurology
- Infectious Diseases
- Cardiology
Background:
- Infectious endocarditis is a known complication in neurologic intensive care units.
- Intracranial hemorrhage is a rare but serious manifestation of infectious endocarditis.
Observation:
- A patient admitted for lumbar radiculopathy developed a large intraparenchymal hemorrhage.
- The patient was retrospectively diagnosed with bacterial endocarditis.
Findings:
- Positive hematoma cultures and transesophageal echocardiogram vegetation confirmed bacterial endocarditis.
- Further evaluation revealed an underlying mycotic aneurysm as the cause of hemorrhage.
Implications:
- This case highlights the importance of considering infectious endocarditis in patients with unexplained intracranial hemorrhage.
- Diagnostic imaging and microbiological investigations are essential for identifying structural lesions like mycotic aneurysms.
- Early recognition and treatment of bacterial endocarditis can prevent severe neurological outcomes.
Abstract:
Infectious endocarditis is frequently found in the neurologic intensive care unit and may rarely be the cause of intracranial hemorrhage. In such instances, further diagnostic imaging to search for an underlying structural lesion is prudent. Well-known causes of these hemorrhages include cardioembolism with hemorrhagic transformation, septic emboli, and mycotic aneurysms. We present a case of a patient who was admitted for routine evaluation and pain management of lumbar radiculopathy, who developed a large intraparenchymal hemorrhage and was found to have bacterial endocarditis. This was diagnosed retrospectively from positive hematoma cultures and a vegetation on transesophageal echocardiogram. Further evaluation revealed a mycotic aneurysm.
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