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A Preclinical Model of Exertional Heat Stroke in Mice
Published on: July 1, 2021
Rhabdomyolysis and Acute Kidney Injury due to Severe Heat Stroke
Máximo H Trujillo1, Carlos Fragachán G1
1Critical Care Department, ICU, Instituto Médico La Floresta (IMLF), Caracas 1060, Venezuela ; Critical Care Department, University Hospital of Caracas, Caracas 1050, Venezuela.
Abstract:
We present a case of heat stroke (HS) and acute kidney injury (AKI) due to severe rhabdomyolysis in a 14-year-old previously healthy female patient. When she was practicing strenuous exercise she suffered acute seizures and high fever. These symptoms were followed by coma and multiple organ failure (MOF), which included AKI, encephalopathy, fulminant hepatic failure (FHF), and disseminated intravascular coagulation (DIC). The patient was managed in the ICU with renal replacement therapy, ventilatory support, and other vital supporting measures. After three weeks of ICU treatment she made a full recovery.
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