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Updated: Apr 29, 2026

Combined In vivo Optical and µCT Imaging to Monitor Infection, Inflammation, and Bone Anatomy in an Orthopaedic Implant Infection in Mice
Published on: October 16, 2014
Clostridium perfringens surgical site infection after osteotomy for knee deformity correction in a
Abdul Halim Abd Rashid1, Ramliza Ramli, Sharaf Ibrahim
11 Department of Orthopaedics and Traumatology, Faculty of Medicine, Universiti Kebangsaan Malaysia , Kuala Lumpur, Malaysia .
Background:
Clostridium perfringens myonecrosis following an elective surgical procedure in a previously healthy child is a rare incident.
Methods:
Case report and literature review.
Results:
A two-year old boy admitted for elective bilateral osteotomies of tibiae was detected to be febrile at day one post-operatively with crepitus felt at his left ankle. An emergency wound debridement was performed followed by a course of antibiotics. Clostridium perfringens was isolated from tissue culture. His wound was later covered with a split-thickness skin graft.
Conclusion:
Clostridium perfringens infection following a surgical procedure in a healthy child is rare. A high index of suspicion is important to recognize this debilitating infection.
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