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Updated: Apr 29, 2026

Preparation, Purification, and Characterization of Lanthanide Complexes for Use as Contrast Agents for Magnetic Resonance Imaging
Published on: July 21, 2011
Americium(iii) and europium(iii) complex formation with lactate at elevated temperatures studied by spectroscopy and
Astrid Barkleit1, Jerome Kretzschmar, Satoru Tsushima
1Institute of Resource Ecology, Helmholtz-Zentrum Dresden - Rossendorf, P.O. Box 510119, 01314 Dresden, Germany. a.barkleit@hzdr.de.
Abstract:
Thermodynamic parameters for the complex formation of Am(iii) and Eu(iii) with lactate were determined with UV-vis and time-resolved laser-induced fluorescence spectroscopy (TRLFS) in a temperature range between 25 and 70 °C. The reaction enthalpy decreased with increasing ionic strength. ATR FT-IR and NMR spectroscopy in combination with density functional theory (DFT) calculations revealed structural details of the Eu(iii) lactate 1 : 1 complex: a chelating coordination mode of the lactate with a monodentate binding carboxylate group and the hydroxyl group being deprotonated.
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