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Pericardial effusion in celiac disease
Farzaneh Ashrafi1, Ali Darakhshandeh2, Mitra Heidarpour3
1Department of Internal Medicine, Hematology and Oncology Section, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Celiac disease, an autoimmune disorder, can present with anemia and edema in adults. Treatment with a gluten-free diet and iron supplements improved symptoms, including pericardial effusion.
Area of Science:
- Gastroenterology
- Immunology
- Cardiology
Background:
- Celiac disease is an autoimmune disorder affecting 1% of the US population.
- While often diagnosed in childhood, celiac disease can manifest in adulthood, frequently with anemia.
- Adult presentations may differ from classic pediatric symptoms.
Observation:
- A 40-year-old female presented with fatigue and lower extremity edema.
- Diagnosis revealed iron deficiency anemia and celiac disease via serological markers and biopsy.
- Incidental finding of asymptomatic pericardial effusion during evaluation.
Findings:
- Treatment with a gluten-free diet and iron supplementation led to symptom resolution.
- Fatigue, peripheral edema, and pericardial effusion decreased significantly post-treatment.
- Echocardiography confirmed the reduction in pericardial effusion.
Implications:
- This case highlights that asymptomatic pericardial effusion can be a manifestation of celiac disease in adults.
- Early diagnosis and management of celiac disease are crucial for resolving associated complications.
- Emphasizes the importance of considering celiac disease in adult patients with unexplained anemia and edema.
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