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Updated: Apr 29, 2026

Z-Scores for Assessing Ovarian Reserve in Young Patients Undergoing Fertility Preservation
Published on: October 25, 2024
[Premature ovarian failure]
Carmen Regina Leal de Assumpção1
1Instituto Estadual de Diabetes e Endocrinologia Luiz Capriglione, Universidade do Estado do Rio de Janeiro.
Abstract:
This article is a review on different aspects of premature ovarian failure (POF) defined as the development of hypogonadism in women before 40 years of age. The review will discuss the etiopathogeny, autoimmune and iatrogenic causes, abnormalities of chromosome X, as well as clinical manifestations, diagnosis, and treatment. Most of the women with this disorder do not have menstrual history, specific of POF development, but infertility associated with the diagnosis is the most problematic aspect of the disease.
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