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Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
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Related Experiment Video

Updated: Apr 29, 2026

The In ovo CAM-assay as a Xenograft Model for Sarcoma
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Synovial chondrosarcoma: a case report.

K K Wu, E R Guise

    Orthopedics
    |May 17, 2014
    PubMed
    Summary
    This summary is machine-generated.

    A rare knee synovial chondrosarcoma was successfully treated in a 34-year-old male. Above-knee amputation led to a long-term cure, exceeding 12 years for this rare bone cancer.

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    Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma
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    Published on: April 11, 2018

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    Last Updated: Apr 29, 2026

    The In ovo CAM-assay as a Xenograft Model for Sarcoma
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    Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma
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    Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma

    Published on: April 11, 2018

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    Area of Science:

    • Orthopedic oncology
    • Surgical pathology

    Background:

    • Synovial chondrosarcoma is a rare, malignant tumor arising from the synovium.
    • Knee joint involvement is common but challenging to manage surgically.

    Discussion:

    • This case highlights the successful management of a large synovial chondrosarcoma in the knee.
    • Aggressive surgical resection, including above-knee amputation, can achieve long-term disease control.

    Key Insights:

    • Early and accurate diagnosis is crucial for effective treatment of synovial chondrosarcoma.
    • Limb salvage versus amputation decisions depend on tumor size, location, and patient factors.
    • A multidisciplinary approach involving orthopedic surgeons and pathologists is essential.

    Outlook:

    • Further research into less invasive treatment options for synovial chondrosarcoma is warranted.
    • Long-term follow-up is critical to monitor for recurrence and metastasis.